Explaining a few discoveries

Potentially Explaining Literature Based Discoveries in Non-Medical Domains

Literature base discovery has been used for many years as a way to identify possible discoveries of related concepts where the concepts have never been mentioned previously in the same document. Linking concepts and the nature of the relationship between the hidden discovery and the linking concepts may be gleaned from the documents using existing relationship extraction techniques. Little has ...

On Explaining Integer Vectors by Few Homogenous Segments

We extend previous studies on NP-hard problems dealing with the decomposition of nonnegative integer vectors into sums of few homogeneous segments. These problems are motivated by radiation therapy and database applications. If the segments may have only positive integer entries, then the problem is called Vector Explanation. If arbitrary integer entries are allowed in the decomposition, then t...

On explaining integer vectors by few homogeneous segments

We extend previous studies on “explaining” a nonnegative integer vector by sums of few homogeneous segments, that is, vectors where all nonzero entries are equal and consecutive. We study two NP-complete variants which are motivated by radiation therapy and database applications. In Vector Positive Explanation, the segments may have only positive integer entries; in Vector Explanation, the segm...

From the Workshop of Discoveries From the Workshop of Discoveries

Single Nucleotide Polymorphisms and Association Studies: A Few Critical Points

Uncovering DNA sequence variations that correlate with phenotypic changes, e.g., diseases, is the aim of sequence variation studies. Common types sequence variations are Single nucleotide polymorphism (SNP, pronounced snip).SNPs are the third-generation molecular marker. SNP represents a DNA sequence variant of a single base pair with the minor allele occurring in more than 1% of a given popula...